Searchable abstracts of presentations at key conferences in endocrinology

ea0038p67 | Clinical practice/governance and case reports | SFEBES2015

IgG4-related hypophysitis: a novel candidate to the hypophysitis spectrum

Vyas Shemin S , Yahia Seifeldin , Lanyon Peter , Page Simon

A 57-year-old gentleman presented with bilateral painless submandibular swelling, and flu like symptoms. A biopsy from the enlarged submandibular gland showed chronic sclerosing sialadenitis with lymphocytic infiltration. Immunohistochemistry showed plasma cells positive for CD79a and IgG4, and a combination of CD4 and CD8 positive lymphocytes. IgG4 levels were significantly raised (3.16 g/l, NR <1.3 g/l). A diagnosis of IgG4 syndrome was made. Chest and abdominal CT imagi...